Antimicrobial activity of azadirachta indica neem against. Brief information of neem azadirachta indica is discussed here. Antidiabetic activity of vinca rosea extracts in alloxan. During the last five decades, apart from the chemistry of the neem compounds, considerable progress has been achieved regarding the biological activity and medicinal applications of neem. Antidiabetic activity of alcoholic extract of neem. Review article biological activities and medicinal properties.
Rjpt diversity and biological activities of endophytic. Totally 5 different fungal strains were isolated and subsequently purified f1f5 using subculturing techniques. The anticarcinogenic activity of azadirachta indica was studied in research by adopting the protocol of 7,12dimethyl benzaanthracene dmbainduced skin papillomagenesis and benzoapyreneinduced forestomach. Azadirachta indica commonly known as neem plant is a medicinal plant which is used in folklore medicine in the treatment of diabetes mellitus, malaria, typhoid, viral and bacterial infections 7.
Pdf study of antidiabetic activities of endophytic fungi. The animals were grouped according to the doses of extracts administered 0mgkg, 200mgkg, 400mgkg and 600mgkg body weight. Azadirachta indica neem leaf extract was taken to test its antifungal activity against three fungal species aspergillus flavus, alternaria solani and cladosporium. Antifungal activity of azadirachta indica against alternaria. The plant is native to asia, but has now naturalized in west africa. Neem azadirachta indica is a member of the meliaceae family and its role as healthpromoting effect is attributed because it is rich source of antioxidant. To prove the validity of traditional medicine the present work has been undertaken to evaluate the antimicrobial screening of leaves of tinospora cordifolia, azadirachta indica and ocimum sanctum against the human bacterial pathogens. It is typically grown in tropical and semitropical regions. Introduction neem is used in traditional medicine as a source of many. Many indian medicinal plants have been scientifically explored for their antidiabetic and antioxidant activities. All parts of neem tree used as anthelmintic, antifungal, antidiabetic, antibacterial, antiviral, contraceptive and sedative. Each part of the neem tree has some medicinal property.
How azadirachta indica is effective for various diseases is listed in repertory format. Leaves, fruits, flowers and stem bark extracts from the siamese neem tree azadirachta indica a. Antimicrobial potential of azadirachta indica against. Juss is the most useful traditional medicinal plant in india. Azadirachta indica is also known as neem tree, margosa tree, nimtree, indiac lilac or neem. Neem has been found to possess chemopreventive potential that can prevent carcinogenesis and thus, help in the management of cancer. Antimicrobial activity in pulp extract of neem azadirachta indica linn. Also used as an insecticide as well as for pesticide. Azad free, dirakht tree, i hind of indian origin which literally means.
The neem tree, azadirachta indica, provides many useful compounds that are used as pesticides and could be applied to protect stored seeds against insects. Antibacterial activity of azadirachta indica neem leaf. India, nepal, pakistan, bangladesh, sri lanka, and maldives. A rewiew on antidiabetic angiospermic plants from the regions of uttarakhand, india 18 surcease with an ic50 value of 12. Description and medicinal uses of azadirachta indica neem. This chemicals are isolated and separate out from the. May 03, 2017 homeopathic medicine azadirachta indica know what are health benefits and medicinal uses of azadirachta indica in homeopathic. Melia azadirachta is well known in india and its neighbouring countries for more than 2000 years as one of the most versatile medicinal plants having a wide spectrum of biological activity. The methanolic whole plant extract at high dose 500 mgkg exhibited significant antihyperglycemic activity than whole plant extract at low dose 300 mgkg in diabetic rats. Biochar feed additive research activities determine aboveground total. Azadirachta indica showed various pharmacological activities and have demonstrated to possess good spermicidal activity also.
Azadirachta indica article about azadirachta indica by the. Diabetes mellitus can be corelated with madhumeha dealt in ayurveda classics. Neem trees also grow in islands located in the southern part of iran. It is one of two species in the genus azadirachta, native to india and burma, growing in tropical and semitropical regions. Pdf therapeutics role of azadirachta indica neem and. In this it is observed in 200 mg concentration 90 percent of mortality rate of aedes aegypti when compared to 150,100 and 50% like 70,40 and 30% respectively figure 5. Family myrtaceae eugenia jambolana, called jamun, black plum or indian black berry, has been more extensively. Introduction antidiabetic drugs treat diabetes mellitus by lowering glucose levels in the blood. Many compounds with different pharmacological activity have been evaluated in vitro for their spermicidal activity. Mar 28, 2020 state tree of andhra pradesh neem azadirachta indica.
Juss meliaceae have been used by folklore for a number of ailments. Medicinal herbal plants and allopathic drugs to treat. Properties and uses of neem, azadirachta indica article pdf available in canadian journal of botany 681. Azadirachta indica, aqueous and organic extracts, hplc, fungal inhibitory effect. The aim of this study is to evaluate the hypoglycemic effect of combination of a. Journal of applied pharmaceutical science, 7, 100105. It is found in various regions of india, srilanka, pakistan and bangladesh. Antimicrobial activity in leaf extract of neem azadirachta indica against human pathogenic bacteria. In this study we used azadirachta indica, ocimum sanctum and citrus limon due to their individual benefits. A huge number of medicinal plants with potential antidiabetic activity have been listed which may include. Comparative antidiabetic effects of the ethanol leaf.
Am eimahmood, ob ogbonna and m raji, the antibacterial activity of azadirachta indica neem associated with eye and ear infections, journal of medicinal plant research, 2010, 414,14141421. Mangoes belong to genus mangifera which consists of about 30 species of tropical fruiting trees in the flowering plant family anacardiaceae. According to ayurveda, varied medicinal properties are attributed to different parts of mango. The latinized name of neem azadirachta indica is derived from the persian. The prime objective of this work is to the study the diversity and activity of endophytic fungus isolated from the azadirachta indica plant. Turmeric, azadirachta indica neem, pterocarpus marsupium kino tree, momordica charantia. Antibacterial activity of azadirachta indica neem leaf extract against bacterial pathogens in sudan hala a. Cronicon open access ec pharmacology and toxicology.
A true multipurpose tree, neem is a very valuable plant to grow. Uses, benefits, cures, side effects, nutrients in azadirachta indica. Antimicrobial activities of alcoholic extracts of neem leaves were used. Azadirachta indica, antimicrobial activity, antifungal activity, pathogenic.
Antinociceptive and antioxidant activities of methanolic. The major constituent is azadirachtin a, and other isomers that may be present include azadirachtin are azadirachtins b, h, and j. Most of the parts of neem tree were studied in details by many researchers but neem root bark was not screened for antidiabetic effect. Background azadirachta indica neem is a communal plant of meliaceae family called neem or kadunimb in maharashtra, india neem stated antiinflammatory through regulation of proinflammatory enzyme activities with cox and lox enzyme. Neem tree azadirachta indica is a tree in the mahogany family meliaceae, is evergreen tree found in most tropical countries. Antifungal and phytochemical properties of tinospora. Neem tree growth and care learn about neem tree benefits. Physical characteristics, chemical composition and. Azadirachta indica an overview sciencedirect topics. Azadirachta indica neem is a multipurpose tree with multiple health benefits. The who has listed 21,000 plants, which are used for. Phytochemical screening and antimicrobial activity evaluation of aqueous and ethanolic extracts of the leaf of azadirachta indica juss neem on some microorganisms itelima et al.
Azadirachta indica herb uses, benefits, cures, side effects. Azadirachta is a genus of two species of trees in the family meliaceae. In vivo antidiabetic effect of aqueous leaf extract of. Kutama3 and lurwanu muazu4 1department of microbiology, federal university gusau, nigeria 2desert research monitoring and control centre, yobe state university damaturu, nigeria 3department of biology, saadatu rimi college of education, nigeria.
Antityphoid activity and phytochemical screening of. Aqueous extract, azadirachta indica leaf, chloroquine sulphate. Pdf antimicrobial activity of azadirachta indica neem. Learn some remedies of azadirachta indica to treat your health problems. A study on antioxidant and apoptotic effect of azadirachta.
This study therefore seeks to examine azadirachta indica for antiinflammatory activity and analgesic effects since pain is one of the cardinal signs of inflammation. About azadirachta indica and economic importance of neem. Full length research article effect ofazadirachta indica leaf. Ingolf grun, dissertation supervisor abstract a significant increase in the health consciousness of people all around the world has rekindled interest in age old medicinal systems such as ayurveda and unani. It is very common to combine two or more types to get the best. Hypoglycemic effect of combination of azadirachta indica a. List of various diseases cured by azadirachta indica. The ethanol extract 250 and 500 mgkg reduced postprandial elevation in blood glucose levels at 30 and 60 min after administration of maltose. Ethanolic and methanolic extracts in different concentrations 25%, 50%, 75% and 100% was prepared and tested against test organisms using disc diffusion method. Phytochemical screening and antimicrobial activity evaluation. Full length research article effect ofazadirachta indica leaf extract onserum lipid profile changes in normal and streptozotocin induced diabetic rats r.
Page 1 of 9 antityphoid activity and phytochemical screening of azadirachta indica leaf extracts muhammad ali1, muhammad s. To study the antioxidant properties of neem azadirachta indica in inducing apoptosis of cervical cancer cells and estimation of caspase activity and tnf. Pharmacological activity of azadirachta indica analgesic effect in a study done by kumar et al. Azadirachta indica, commonly known as neem, nimtree or indian lilac, is a tree in the mahogany family meliaceae. The herbal drugs with antidiabetic activity are extensively formulated commercially because of easy availability, affordability and less side effects as compared to the synthetic antidiabetic drugs.
Pdf feeding trials in organic food quality and health research. Molecular approach to identify antidiabetic potential of. Evaluation of allelopathic potential of neem azadirachta indica. This versatile plant, native to tropical india and asia, is a valuable tree with many uses. The therapeutic and pharmacological properties of azadirachta indica are widely known. Experimentation was made to evaluate the antioxidant activity of the flowers and seed oil of neem plant azadirachta indica a. Azadirachta indica is now used in traditional medicine as a source of many therapeutic agents. Antimicrobial activity of azadirachta indica neem leaf, bark and seed extracts. Names of azadirachta indica in various languages of the world are also given. Study of antidiabetic activities of endophytic fungi. Juss family meliaceae is well known in india and its neighboring countries as one of the most versatile medicinal plants having wide spectrum of biological activity. Mar 01, 2016 neem azadirachta indica is a member of the meliaceae family and its role as healthpromoting effect is attributed because it is rich source of antioxidant. It is one of two species in the genus azadirachta, and is native to the indian subcontinent, i.
The herbal drugs with antidiabetic activity are extensively formulated. Antimicrobial activity, azadirachta indica, pathogenic bacteria, leaf and bark extract. The plant, azadirachta indica a juss, family meliaceae is a native of asia but has now naturalized in west africa and is widely cultivated in nigeria as an ornamental as well as medicinal plant. Department of botany, lahore college for women university, lahore, pakistan. Neem is a renewable resource of various useful domestic and agricultural products, including cattle feed, medicines, soap industry, nitrification inhibition, slow nutrient release manure, fuel, energy, pest control, and others. Varying concentration of each extracts 200mgml, 150 mgml, 100mgml. In this study, total phenolics, flavonoids and vitamin c content visavis antioxidant activities were assayed in leaves and stem bark of azadirachta indica, butea monosperma, cassia fistula. It is a fast growing tree, average height 1520 m but rarely to 3540 m. The studies showed that smcs and sacs exerted their antidiabetic properties by stimulating insulin secretion as well as compete with insulin for insulin inactivating sites in the liver. Materials and methods plant material the leaves of azadirachta indica were collected in december 2010 from bhubaneswar, odisha.
Neem azadirachta indica introduction neem or margosa is a botanical cousin of mahogany. It has been widely used in chinese, ayurvedic, and unani medicines worldwide especially in indian subcontinent in the treatment and prevention of various diseases. Therapeutical and medicinal properties of neem azadirachta indica in context of unani system of medicine. P1 lecturer, department of kuzhandhai maruthuvam, sivaraj siddha medical college, salem636307. Pdf therapeutical and medicinal properties of neem. Leaves seeds flowers fruits bark roots some of the chemicals or the active constituents which can be separate out are as follows. Faculty of medical laboratory sciences, al neelain university, khartoum, sudan. Azadirachta indica its leaves, stem bark and seeds possess hypoglycemic activity via increasing insulin secretion from pancreatic betacells, grewia asiatica its antioxidant and radical scavenging activity, eugenia jambolana its seed. The results showed that the methanolic extract of artemisia herbaalba exhibited prominent antimycoplasmal activity at 30 mg by producing maximum zone of inhibition 15. Provided by smithsonian institution, department of botany. Biological and pharmacological activities attributed to different parts and extracts of these plants include antiplasmodial, antitrypanosomal, antioxidant, anticancer, antibacterial, antiviral, larvicidal and fungicidal activities. Homeopathic medicine azadirachta indica homoeopathy. It is one of two species in the genus azadirachta, and is native to the indian subcontinent. Ethanol extracts of mangifera indica, azadirachta indica and petroleum ether extract of murraya koenigii at a concentrations 10100.
About azadirachta indica active constituents of neem. The present study was carried out to evaluate the antidiabetic activity of vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. Because of these activities neem has found enormous applications making it a green treasure. Formulation, evaluation and antibacterial efficiency of. Previous studies show that azadirachta indica neem and its chief constituents play essential role in anticancer management via the modulation of different. All parts of azadirachta indica are used in many medicinal treatments like. It has been reported to have antimutagenic 22, antidia. It has shown significant antiinflammatory, analgesic and antipyretic activity. It may also known herbs used for madhumeha in ayurveda. Some of the active constituents of neem azadirachta indica are as follows. Pdf properties and uses of neem, azadirachta indica. Neem is a fastgrowing tree that can reach a height of 1520 m, rarely to 3540 m.
Is a combine therapy of aqueous extract of azadirachta indica leaf. Therapeutics role of azadirachta indica neem and their. Development of new antidiabetic drug from medicinal plant. The neem tree azadirachta indica has caught the attention of gardeners in recent years for the benefits of its oil, a safe and effective herbicide. Gcms chromotogram of metahanol leaf extract of azadirachta indica. This study was aimed to isolate and evaluate endophytic fungi from different plants like mango mangifera indica coded as man, mbr, neem azadirachta indica indicated as ngu and nth and jambolan syzygium cumini l shown as jco, jgr, jgy for their antidiabetic potentials. Exploration of plant combinations could be an alternative approach for diabetes treatment. Bandyopadhyay agricultural sciences unit, indian statistical institute, 203, barrackpore trunk road, kolkata 700 108, india. Neem, margosa soitfsm70 february uhm meliaceae mahogany family john a. Preliminary phytochemical screening and in vitro anti. The present study was undertaken to evaluate the 70% alcoholic neem root bark extract nre in diabetes. Mangifera indica mi, also known as mango, aam, it has been an important herb in the ayurvedic and indigenous medical systems for over 4000 years. Numerous species have been proposed for the genus but only two are currently recognized, azadirachta excelsa and the economically important tree azadirachta indica, the neem tree, from which neem oil is extracted. Antifungal activity of leaf extract of neem azadirachta indica linn.
The most important active constituent is azadirachtin and the others are nimbolinin, nimbin, nimbidin, nimbidol, sodium nimbinate, gedunin, salannin, and quercetin. Meliaceae is a woody family of plants comprising 50 genera and about 640 species widely distributed throughout the tropics and subtropics, with only slight penetration into temperate zones muellner et al. To evaluate antidiabetic effect of neem root bark this study was conducted. Nimtree and indian lilac is a tree in the mahogany family meliaceae. The comparative antidiabetic effects of ethanol leafextracts of vernonia amygdalina and azadirachta indica were conducted. Since neem contains a number f o activity are present in many plants and in many organs, useful compounds with multiple uses and adapts including leaves, stems, flowers, fruits and buds 24. The antimicrobial activity of azadirachta indica, mimusops. Azadirachta indica, commonly called neem or dogonyaro in nigeria, is a plant that has found varied use in ecological, medicinal and agricultural sectors. Safety evaluation of neem azadirachta indica derived pesticides. Antifungal activity of azadirachta indica against alternaria solani. It is a very effective medicinal herb, provides food, timber, a very good insecticide and repellent and many other commodities.
The physical characterization revealed an average seed weight of 0. Traditional medicines derived from medicinal plants are used by about 60% of the worlds population. Antimicrobial potential of azadirachta indica against pathogenic. State tree of andhra pradesh neem azadirachta indica. Azadirachta indica neem, persian lilac, indian lilac, paradise tree, bead tree, cornucopia, margosa family meliaceae. To check the antimicrobial activity of azadirachta indica neem, ocimum sanctum tulsi, mimusops elelngi bakul, tinospora cardifolia giloy and chlorhexidine gluconate chx on common endodontic pathogens like streptococcus mutans, enterococcus faecalis and staphylococcus aureus. Azadirachta indica neem is perhaps the most useful traditional medicinal plant. Juss collected in southwest senegal were characterized. A rewiew on antidiabetic angiospermic plants from the. Effect of neem azadirachta indica on the survival of. Azadirachtin has structural similarity to the class of insect hormones known as ecdysones and.
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